The impact of policy interventions to promote the uptake of biosimilar medicines in Belgium: a nationwide interrupted time series analysis

Table 4 ARIMA modelling parameter estimates of filgrastim (L03AA02)

Parameter	Estimate*	Standard error (SE)	95% Confidence interval (CI)	P-value
Step change for intervention 1	1809.833	232.161	1354.797 to 2264.869	< 0.001
Ramp for intervention 1	−151.639	26.270	−203.128 to −100.150	< 0.001
Step change for intervention 2	700.932	265.508	180.536 to 1221.328	0.016
Ramp for intervention 2	−62.004	110.784	−279.141 to 155.133	0.582

ARIMA specification (0,1,0); R² = 0.998; Ljung–Box Q estimate = 14.182 (P = 0.717). *No transformation has been performed

ISSN: 1478-4505