Table 1 Population subsystem parameters and assumptions
From: Advancing the application of systems thinking in health: why cure crowds out prevention
Equilibrium parameters | Variable type | Initial value | Notes and assumptions |
|---|---|---|---|
Susceptible population | State | 800 | Individuals |
Disease A infection rate | Rate | 40 | Individual infected/year |
Disease A patients | State | 200 | Infected population, at equilibrium |
Disease A incidence rate | Auxiliary | 0.05 | Population based incidence |
Disease A duration | Auxiliary | 0.2 | Years |
Disease A recovery rate | Rate | 40 | All infected with disease A, recover |
Death from disease B | Rate | 4 | Deaths/year |
Accumulated death from disease B | State | 0 | Deaths from B, at equilibrium |
Disease A annual burden | Auxiliary | 100 | Disease A burden at equilibrium |
DALYs lost per case of disease A | Auxiliary | 0.5 | Constant – one untreated case of infection with A is equivalent to 0.5 years of life with disability |
Disease A cumulative burden | State | 0 | Disease A burden at equilibrium |
Disease B annual burden | Auxiliary | 100 | Disease B burden at equilibrium |
DALYs lost per case of disease B | Auxiliary | 25 | Constant – one death from B is equivalent to 25 years of life lost |
Disease B cumulative burden | State | 0 | Disease B burden at equilibrium |
Total cumulative disease burden | Auxiliary | 0 | Sum of cumulative burden for disease A and disease B, at equilibrium |