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Table 3 Validation results by parallel testing with the National TB Reference Laboratory (NTRL) as reference (n = 14)

From: Feasibility of establishing a biosafety level 3 tuberculosis culture laboratory of acceptable quality standards in a resource-limited setting: an experience from Uganda

Current laboratory

NTRL

 

Test method

Results

Positive

Negative

Total

Smear microscopy

Positive

7

0

7

 

Negative

1

6

7

 

Sensitivity

 

87.5

 

Specificity

 

100

 

Kappa

  

0.9

Sputum culture (MGIT)

Positive (MTBc)

7

0

7

 

Negative

1

6

7

 

Sensitivity

 

87.5

 

Specificity

 

100

 

Kappa

  

0.9

Sputum culture (LJ)

Positive (MTBc)

6

0

6

 

Negative

1

7

8

 

Sensitivity

 

85.7

 

Specificity

 

100

 

Kappa

  

0.9

  1. LJ, Lowenstein-Jensen; MGIT, Mycobacterial growth indicator tube; MTBc, Mycobacterium tuberculosis complex.