Table 1 Checklist for identifying guidelines requiring adaptation
Factors influencing the applicability or transferability of guidelines across different settings | Response (positive answers increase the likelihood that recommendations should be flagged as requiring adaptation) |
|---|---|
1. Is there important variation in need (prevalence, baseline risk or health status) that might lead to different decisions? | □ Yes □ Unclear □ No |
2. Is there important variation in the availability of resources that might lead to different decisions? | □ Yes □ Unclear □ No |
3. Is there important variation in costs (e.g. of drugs or human resources) that might lead to different decisions? | □ Yes □ Unclear □ No |
4. Is there important variation in the presence of factors that could modify the expected effects (e.g. resistance patterns of microbiological pathogens), which might lead to different decisions? | □ Yes □ Unclear □ No |
5. Is there important variation in the relative values of the main benefits and downsides that might lead to different decisions? | □ Yes □ Unclear □ No |