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Table 4 Overview of funding distribution mechanisms of the 10 largest funding organizations of health research globally (in million 2013 US $)

From: The 10 largest public and philanthropic funders of health research in the world: what they fund and how they distribute their funds

 

1

2

2a

2b

3

4

5

5a

6

7

8

9

10

Funding organization

NIH

EC – total

EC – FP7 health

EC – ERC

MRC

Insermb

US DoD – total

US DoD – CDMRP

Wellcome Trusta

CIHR

NHMRC

HHMI

DFG

Country

USA

EU

EU

EU

GBR

FRA

USA

USA

GBR

CAN

AUS

USA

DEU

Total health research funding

26,081.3

3717.7

1181.7

783.4

1321.5

1041.2

1017.7

409.0

909.1

883.6

777.6

752.0

630.6

Year

2013

2013

2013

2013

2013

2013

2013

2012

2013

2012

2013

2013

2012

Intramural vs. extramural

Largely extramural

NA

Extramural

Extramural

Mixed

Intramural

NA

Largely extramural

Largely extramural

Extramural

Extramural

Largely extramuralc

Extramural

Mechanism for extramural funding

Largely untargeted (but earmarked for broad areas), with smaller targeted and organizational funding streams

NA

Targeted, issuing calls under prioritized health research topics

Untargeted

Mixed approach, with large streams for untargeted (but earmarked for broad areas), targeted and organizational fundingd

NA

Largely targeted, issuing calls under prioritized health research topics, with a smaller untargeted funding stream

Largely untargeted, with a smaller targeted funding stream

Largely untargeted, with a smaller targeted funding stream

Largely untargeted, with smaller organizational and targeted funding streams

Untargeted

Mixed approach, with large streams for organizational and untargeted funding and a smaller targeted funding stream

Intramural funding

3283

0

0

0

513

1041

16

155

0

0

100

0

Extramural funding

22,799

3718

1182

783

809

0

393

754

884

778

652

631e

 Project grants

18,341

1182

783

519

0

368

692

478

0

271

  Untargeted

0

0

783

0

0

0

464

468

0

217

  Untargeted, earmarked for broad areas

11,708

0

0

220f

0

0

0

0

0

0

  Targeted

3738

1182

0

221f

0

299

228

0

0

52

  Highly targeted

2895

0

0

0

0

69

0

10

0

2

 ‘People grants’

615

0

0

98

0

25

105

156

652

14

 All funding to organizations

2709

0

0

163

0

0

4

143

0

254

 Other researchg

1134

0

0

28

0

0

83

0

0

1

 Research training/science educationh

768

0

0

0

0

26

64

0

80

38

  1. All data are from publicly available documents, except for CDMRP and DFG, for which data were received through personal communication, and for CIHR for which the data were largely publicly available but were supplemented through personal communication
  2. Zero’s (“0”) indicates an amount of zero million in funding; dashes (“–”) indicate that no information on the amount of funding was available; NA indicates that we did not extract information for overarching funding organizations (only for the more specific organization(s) next to it). Some of the funders we identified (the EC and the US DoD) consisted of several sub-organizations that distributed the research funding in different ways, in which case we compiled total funding for the organization as a whole, but analysed the distribution mechanisms of the largest sub-organization(s)
  3. NIH, National Institutes Of Health; EC, European Commission; FP7 health, FP7-cooperation programme – Health Theme; ERC, European Research Council; US DoD, United States Department Of Defense; CDMRP, Congressionally Directed Medical Research Program; MRC, Medical Research Council; Inserm, Institut national de la santé et de la recherche médicale; CIHR, Canadian Institutes Of Health Research; NHMRC, National Health and Medical Research Council; HHMI, Howard Hughes Medical Institute; DFG, Deutsche Forschungsgemeinschaft
  4. aThe annual expenditures for the Wellcome Trust are a slight overestimation for health research spending. Under medical humanities and engagement, various non-research grants are provided as well as other activities (e.g. running the Wellcome library), but these were not reported on separately, so are included under ‘Research’
  5. bInserm funds research almost exclusively intramurally. However, Inserm does provide for some extramural funding. We were not able to find any information about the proportion of funding by Inserm that is distributed extramurally, but it is likely very small, so we classified all of Inserm’s funding as intramural. Historical research into Inserm’s expenditures put the organization’s intramural/extramural proportions of distributed funds at 10/90 [23]
  6. cTechnically, HHMI funds research 100% intramurally because it employs its own researchers. However, its researchers are mostly located at external research institutes or universities (with the exception of HHMI’s Janelia Research Campus), and therefore, for this table, we classified HHMI’s funding distribution mechanism as largely extramural. The 100 million dollar for intramural funding is based on an annual budget estimate from 2010 for the Janelia Research Campus by HHMI itself and is not a precise number
  7. dThe MRC has both untargeted and targeted funding streams; most are untargeted (‘response-mode’ in the MRC’s description). However, untargeted funding at the MRC is not fully untargeted, the Research Boards that make funding decisions take into account broader strategic considerations, priorities, portfolio balance, and issue ‘highlight notices’ for issues that are of especial importance to the MRC
  8. eThe data for DFG do not add up because multiple sources were used (public reporting and personal communication). The total amount of funding includes overhead costs for projects, while amount for various research categories are exclusive of overhead costs
  9. fFunding distribution figures of MRC are based on data provided in the annual report 2013/2014 of the MRC United Kingdom. All figures are based on actual expenditures; however, targeted and untargeted funding are based on commitments made, and therefore do not add up to total Project funding
  10. g‘Other research’ included ‘other research’ categories in funding organizations’ reports and funds for research communication when specified separately
  11. hTraining support and research education were not included in the overall amount for health research expenditures, but because there can be an overlap between these activities and research activities, particularly in the case of post-doctoral fellowships, we collected expenditures toward research education and training separately
  12. For definitions of terms in this table (e.g. ‘people grants’ or ‘untargeted’/‘targeted’/‘highly targeted’) see Additional file 1