Table 6 Internal rate of return: one way sensitivity analyses

Best Estimate

6.8%

Low research spend (£12 m)

7.6%

High research spend (£16 m)

6.0%

Omit length of stay reduction

5.5%

QALY £13 k

0.8%

QALY £20 k

5.0%

QALY £30 k

8.1%

QALY £60 k

12.9%

Long lag (20 years)

5.5%

Short lag (11 years)

8.1%

Low attribution to United Kingdom (20%)

4.5%

NMB −25%

5.1%

NMB +25%

8.0%

Royalty payments to public/charitable funders

7.0%

Total royalty payments

7.2%