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Table 6 Internal rate of return: one way sensitivity analyses

From: Estimating the returns to United Kingdom publicly funded musculoskeletal disease research in terms of net value of improved health outcomes

  IRR
Best Estimate 6.8%
Low research spend (£12 m) 7.6%
High research spend (£16 m) 6.0%
Omit length of stay reduction 5.5%
QALY £13 k 0.8%
QALY £20 k 5.0%
QALY £30 k 8.1%
QALY £60 k 12.9%
Long lag (20 years) 5.5%
Short lag (11 years) 8.1%
Low attribution to United Kingdom (20%) 4.5%
NMB −25% 5.1%
NMB +25% 8.0%
Royalty payments to public/charitable funders 7.0%
Total royalty payments 7.2%
  1. IRR internal rate of return, QALY quality adjusted life years, NMB net monetary benefit