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Table 4 Ranked technical issues, presented as groups of related issues and by rank

From: Identifying priority technical and context-specific issues in improving the conduct, reporting and use of health economic evaluation in low- and middle-income countries

Priority rank

Technical issue

Score

Frequency in first rank

Lack of relevant data

1

Lack of high-quality local clinical data, where such data are critical to the decision

80

21%

3

Insufficient data to conduct study from chosen perspective

57

9%

5

Absence of locally relevant health state preference data suitable for estimating QALYs or DALYs

43

7%

Lack of commonly accepted standard or methods

2

Poor reporting

67

21%

4

A lack of commonly accepted standards for economic evaluation that is relevant to the LMIC for which the analysis is undertaken

57

19%

Inappropriate use of methods

6

Inappropriate choice of comparator(s)

29

7%

7

No budget constraints or thresholds considered

26

5%

8

Generalisability not discussed

14

3%

10

Equity and/or gender implications not considered

12

0%

11

No incremental analysis

11

1%

12

No, or inappropriate, sensitivity analysis

10

0%

13

All impacts implied by the chosen perspective not investigated

10

3%

15

Time horizon too short to capture relevant costs and health effects

9

1%

Inappropriate use of data

9

Clinical data not based on systematic review or primary clinical data not compared with similar studies done elsewhere

12

1%

14

Uncritical use of charges for cost data

9

1%