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Table 1 The research impact matrix for the Centre for Research Excellence in Cardiovascular Outcomes Improvement projects

From: Applying a framework to assess the impact of cardiovascular outcomes improvement research

Time frame

Impact categories

Impact subgroups

Outputs/outcomes

Short-term

1. Research-related impact

Research and innovation outcomes

Direct

Peer-reviewed publications (n = 41)

Number of citations (n = 87)

Journal impact factor (median 2.843; range 1.248 to 23.239)

Manuscripts under review or development (n = 26)

Indirect

Associated publications (n = 156)

Dissemination and knowledge transfer

Direct

Conference presentations (n = 61)

Total PhD candidacies commenced (n = 7):

  PhD candidacies with cross-institutional collaboration (n = 1)

Academic collaborations, research networks and data sharing

Direct

Total new academic collaborations (n = 5):

  International collaborations (n = 3)

New database linkages (n = 6):

  Admitted episodes & emergency episode

  National Death Index

  Ambulance Victoria

  Australian and New Zealand Society of Cardiac and Thoracic Surgeons National database

  Combined Australian acute coronary syndrome registries (n = 16,500)

  Development of a multistate linked data platform for analysis of coronary heart disease in younger adults

Indirect

Utilization and reinforcement of a national general practice network to conduct research (> 2000 members)

Establishment of the Australian and New Zealand Alliance for Cardiovascular Trials network (> 200 members)

Mid-term

2. Influencing and involvement in policy-making

Level of policy-making

Indirect

Centre contribution to the development of a national cardiac data registry

Centre contribution to the development of the National Heart Foundation guidelines [35,36,37]

Type and nature of policy impact

Direct

Contribution to Medicare Benefits Schedule reimbursement item number application:

  Ambulatory blood pressure monitoring

Implementation of patient reported outcome measures in several data registries:

  Coronary Angiogram Database of South Australia

Victorian Cardiac Outcomes Registry

Policy networks

Direct

Establishment of new industry collaborations (n = 9)

Embedded academic and statistician roles in industry

  Western Australian Department of Health

PhD candidate transition to industry role (n = 1)

Long-term

3. Health and health systems impact

Evidence-based practice

Direct

Establishment of longitudinal data capture regarding change in practice:

  Coronary Angiogram Database of South Australia [38]

  Percutaneous coronary intervention [39]

  Door-to-balloon time [40]

  Coronary artery bypass graft surgery [41]

Development of contemporary management for aortic stenosis [42, 43]

Development of a risk prediction model linked with cardiovascular data registries, which is reportedly used ongoing and has directly impacted hospital care [44, 45]

Quality of care and service delivery

Direct

Validation and auditing of registry data so it can be used to improve quality of care and service delivery:

  Coronary Angiogram Database of South Australia

  Melbourne Interventional Group database [46]

  Australasian Society of Cardiac and Thoracic Surgeons database [46]

Prevention targets developed from the identification of risk factor burden, clinical profile, and morbidity patterns of adults < 55 years with acute coronary syndrome

Cost containment and effectiveness

Direct

Cost-effectiveness of surgery vs stenting established:

  Percutaneous coronary intervention vs surgery for the treatment of multivessel coronary artery disease in the drug-eluting stent era [47]

  Coronary artery bypass surgery vs stenting in high-risk patients [48]

  Guideline-driven use of drug-eluting stents [49]

Resource allocation

No information identified

Health workforce

No information identified

4. Health-related and societal impacts

Health literacy

No information identified

Health knowledge, attitudes and behaviours

No information identified

Improved social equity, inclusion or cohesion

No information identified

5. Broader economic impacts

Economic impacts

Direct

PhD candidates transitioned from centre-funded to externally funded scholarship (n = 6; AUD$300,586)

Centre grant recipients awarded additional external research funding:

  National Health and Medical Research Council (total AUD$2,481,816)

  Medical Research Future Fund (total AUD$2,062,697)

Leveraged industry grants (n = 2):

 Emergency Medicine Research Foundation (AUD$150,000)

National Heart Foundation Vanguard Grant (AUD$73,000)

  1. The term industry refers to all non-academic organizations, including governmental, non-governmental, and private