Skip to main content

Table 3 Pros and cons of using the same system for grading evidence and formulating recommendations for a wide range of health care interventions, including clinical and non-clinical interventions

From: Improving the use of research evidence in guideline development: 9. Grading evidence and recommendations

Arguments for having a common approach

Arguments against having a common approach

• Having less demanding systems for some kinds of questions might result in false positive conclusions.

• People with vested interests in particular interventions could choose the system that makes their intervention look best.

• People with vested interests in particular evaluation approaches could choose the system that makes their preferred evaluation approach look best.

• Having different systems for different types of interventions might be confusing.

• It is intellectually honest to recognise the limits of evidence where this is appropriate.

• Admitting the limitations of evidence, if this is appropriate, might promote more and better research.

• Having an infeasible system for some kinds of questions might result in false negative conclusions.

• False negative conclusions due to inappropriate evaluation requirements may have negative political and health consequences; for example, effective programs that cannot be studied with randomised trials might experience funding cuts.

• Interventions that cannot be studied with randomised trials might not be evaluated.

• A single system may not discriminate adequately within the range of evidence that is appropriate to consider for clinical and non-clinical interventions.

• A system that can adequately address evidence across a wide range of interventions and contexts may be overly complex.