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Table 1 Criteria for setting priorities according to their assessed importance by participants and external stakeholders.

From: Prioritization strategies in clinical practice guidelines development: a pilot study

Domain Items Mean participants'
weighted score (SD)
Disease Burden - Disease/Condition incidence or prevalence
- High risk impact of disease/condition in the health system
- High frequency of risk factors associated with the disease/condition
- High frequency of avoidable risk factors associated with the disease/condition
80,8 (18,2)
Information needs in the Health Sector - Information needs within the Institution/Organization
- Current controversy about topic importance
- High importance of new methods and technology assessment
- Fast diffusion of non-assessed technologies, availability of resources and sufficient time for technologies implementation
- Country health priorities in agreement with CPG's needs
- High impact on national health system
Feasibility on development and implementation - Feasibility on recommendations development which will improve health outcomes and cost
- Is the proposal politically feasible?
- Does it belong to priority health areas according to government policies?
- Feasibility in implementation; will not require an excessive amount of resources and will not present important barriers to implement changes
- Will reduce inequities when implemented
- Will require education to training professionals
- Does the proposed topic include the participation of multiple departments, institutions, organizations, etc?
Effectiveness - Availability of effective methods shown by methodologically adequate studies.
- Certainty about effectiveness of assessed interventions and technologies
- Potential impact of CPG
71,2 (20,7)
Economic impact on the health system - Economic effects on health system (cost of an individual patient is high during diagnosis or therapeutic process)
- Disease/Condition associated with iatrogenic interventions that are significantly high in cost.
69,8 (24,0)
Clinical Practice Variation - Current evidence is insufficient for disease control in the population
- Lack of high quality CPGs
- Availability of high volume of evidence regarding the CPG topic
- Evidence of inappropriate use of available technologies used in the treatment of condition (iatrogenic)
- Conditions/diseases where effective treatments could reduce mortality or morbidity
- Evidence of disagreements between current treatment and literature recommendations.
68,0 (22,1)
Other social effects/Equity - Absenteeism from work or school, inability to work, inequities in access to health services
- Will the service be available to anyone who requires it?
- Will this CPG have a positive or negative impact on minorities' access to health services?
- Will the CPG increase health service access to those affected by the condition?
67,2 (25,7)
User Preferences - High patient demand or interest
- Concerns about patients' quality of life
- Feasibility of patient empowerment
- High acceptability of the topic between the general public and professionals affected by the use of the CPG.
64,9 (22,3)
Adverse events - Possibility of adverse events
- Possibility of serious adverse events
- Disease/condition associated with high incidence of adverse events or sequels
57,1 (28,0)
Health Promotion and Disease Prevention - Feasibility of prevention between patients with risk factors
- Are there specific activities of health promotion, disease prevention, early diagnosis or treatment? Have all of them shown a reduction in disease burden?
56,4 (32,3)
  1. * The maximum score was 100 and the minimum was 0