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Table 3 Intervention studies (Change in costs due to moving from incorrect to correct management)

From: Do clinical guidelines reduce clinician dependent costs?

Reference/Design

Country/setting

Inclusion criteria/intervention

Degree of financial saving

LOE

Adam et-al. (2005); Comparative study[11]

Tanzania

Districts with Integrated Management of Childhood Illness (IMCI) against those without

Cost per child in IMCI district was 44% lower than in district without IMCI. Although drug costs were higher by 61% in IMCI districts

2b

Hogg et-al. (2005); Randomized control trial[24]

Ontario Canada

Multifaceted intervention to improve preventive care delivered by nurses

Savings from a reduction in inappropriate testing were 35% of total health system costs

1b

Ripouteau et-al. (2000); A controlled prospective before and after study[17]

France

Multifaceted intervention to promote early switch from acetaminophen for prospective pain intravenous to oral

Mean cost per patient for analgesia decreased from £14 to £6 after the intervention to a 57% decrease

2a

Boyter et-al. (1995); Before and after study[19]

Britain

New antibiotic protocols, involving Amoxicillin as a first line agent

Mean consumable cost per patient reduced significantly from £14-09 to £10.20 this translates to a 28% reduction

1b

Palmer et-al. (2000); Cluster randomized Control trial[25]

Canada

Use of a critical pathway designed to manage community-acquired pneumonia more efficiently than conventional therapy

The pathway produced cost savings of 16%, 24% and 24% for the three perspectives respectively

1b

  1. LOE: Oxford centre for Evidence-Based Medicine level of evidence (May 2001)[10]