Fig. 1From: Setting priorities in health research using the model proposed by the World Health Organization: development of a quantitative methodology using tuberculosis in South Africa as a worked exampleWHO model for ranking of research priorities [8]. Ability to tackle the burden of disease is represented by the efficacy of interventions, and the coverage in the population. Improvements in coverage can be gained via either health systems research or biomedical research to reduce the cost of interventions. Efficacy gains can arise from research to identify new interventionsBack to article page