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Table 4 Mean and 95% confidence intervals (CIs) for costs, mortality and QALYs, at 90 days and 10 years for Greater Manchester (GM) per 1000 patients

From: The potential role of cost-utility analysis in the decision to implement major system change in acute stroke services in metropolitan areas in England

 

Greater Manchester

England

DID

Before

After

Difference

Before

After

Difference

90-day results

 Deaths

127 (103 to 151)

102 (76 to 127)

−25 (−46 to −5)

130 (109 to 152)

103 (84 to 121)

−27 (−33 to −22)

2 (−19 to 23)

 LOS

20 (19 to 22)

16 (14 to 17)

−6 (−6 to −4)

19 (18 to 21)

17 (16 to 18)

−3 (−3 to −2)

−2 (−3 to −1)

 QALYs

96 (90 to 102)

103 (93 to 113)

7 (−1 to 15)

98 (92 to 104)

103 (97 to 110)

6 (5 to 6)

2 (−7 to 10)

 Costs

£5,589,377 (£4,441,146 to £6,737,608)

£5,214,732 (£4,263,891 £6,165,572)

–£374,645 (−£740,668 to –£8622)

£5,435,973 (£4,339,780 to £6,532,166)

£4,905,210 (£3,902,177 to £5,908,243)

–£530,764 (−£653,699 to –£407,828)

£156,119 (−£169,632 to £481,869)

10-year results

 Deaths

426 (360 to 492)

399 (329 to 468)

−27 (−44 to −9)

429 (364 to 494)

406 (333 to 479)

−23 (−51 to 6)

−4 (−32 to 24)

 QALYs

2751 (2336 to 3167)

3285 (2906 to 3664)

534 (113 to 954)

2747 (2339 to 3156)

3263 (2882 to 3644)

516 (103 to 929)

18 (−122 to 158)

 Costs

£39,444,918 (£34,251,242 to £44,638,594)

£37,087,053 (£26,978,822 to £47,195,284)

–£2,357,865 (−£6,381,868 to £1,666,137)

£39,092,117 (£29,011,793 to £49,172,441)

£37,205,099 (£26,931,764 to –£47,544,760)

–£1,887,018 (−£5,662,138 to £1,888,103)

–£470,848 (−£1,882,646 to £940,951)

 NMB £20,000 per QALY (per patient)

  

£13,033 (£1244 to £24,822)

  

£12,199 (£674 to £23,723)

£834 (−£1683 to £3350)

  1. LOS length of stay, QALYs quality adjusted life years, DID difference-in-difference, NMB net monetary benefit