Table 1 Selected trial metrics and management of patients by type of stroke research centre
All United Kingdom (n = 774) | HSRC (n = 502) | Non-HSRC (n = 272) | p value | |
|---|---|---|---|---|
Number of recruiting centres (n) | 33 | 9 | 24 | |
Monthly recruitment rate (median, IQR) | 1.0 (0.6–1.5) | 1.5 (1.4–2.2) | 0.7 (0.5–1.3) | 0.01 |
Time from stroke onset to treatment, mins (median, IQR) | 139 (110–175) | 135.5 (110–178) | 140.0 (111–174) | 0.65 |
Time from randomisation to treatment, mins (median, IQR) | 2.8 (0.2–5.4) | 2.6 (−0.6 to 5.3) | 3.1 (1.1–5.7) | 0.01 |
Alteplase given (n/N, %) | 765/774 (98.8) | 498/502 (99.2) | 267/272 (98.2) | 0.20 |
Cerebral angiogram (n/N, %) | 22/774 (2.8) | 20/502 (4.0) | 2/272 (0.7) | 0.009 |
Occluded vessel (n/N, %) | 18/22 (81.8) | 17/20 (85.0) | 1/2 (50.0) | 0.22 |
Endovascular therapy (n/N, %) | 16/22 (72.7) | 15/20 (75.0) | 1/2 (50.0) | 0.45 |