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Table 3 Association between trial characteristics, KT strategies and trial impacts

From: Increased use of knowledge translation strategies is associated with greater research impact on public health policy and practice: an analysis of trials of nutrition, physical activity, sexual health, tobacco, alcohol and substance use interventions

Characteristic Category level At least one impact (n = 66) n (%) or mean (SD) Unadjusted OR (95% CI) Adjusted OR (95% CI)a p-value from adjusted model
Trial effectiveness Lacks evidence of effectiveness 6 (55%)    0.57
Effective 43 (62%) 1.38 (0.38, 4.97) 0.99 (0.19, 5.12)  
Potentially effective 17 (77%) 2.83 (0.60, 13.35) 1.98 (0.28, 13.93)  
Risk of bias High risk or unclear 44 (67%)    0.64
Low risk 22 (61%) 0.79 (0.34, 1.83) 1.31 (0.43, 4.01)  
Setting Community and worksites 9 (41%)    0.056
Medical and other 8 (67%) 2.89 (0.66, 12.57) 3.03 (0.49, 18.75)  
Education 49 (72%) 3.73 (1.37, 10.14) 5.03 (1.34, 18.83)  
Health behaviour Nutrition and physical activity 35 (61%)    0.89
Sexual risk and substance use 31 (69%) 1.39 (0.61, 3.18) 1.07 (0.40, 2.88)  
Total KT score   4.49 (2.04) 1.25 (1.00, 1.56) 1.30 (1.02, 1.66) 0.031*
Individual domain scores
 Involvement of end-users   43.4 (22.8) 1.01 (0.99, 1.03)   
 Adapt knowledge to the local context   66.6 (26.9) 1.00 (0.99, 1.02)   
 Assess barriers to knowledge use   61.3 (30.0) 1.01 (0.99, 1.02)   
 Support to tailor and implement interventions   76.0 (24.0) 1.02 (1.00, 1.03)*   
 Evaluate outcome and monitor knowledge use   68.7 (20.1) 1.02 (1.00, 1.04)   
 Products and tools   59.5 (20.3) 1.05 (1.02, 1.08)*   
 Sustain knowledge use   69.8 (20.6) 1.02 (1.00, 1.03)   
  1. *p < 0.05
  2. aModel adjusted for trial effectiveness, risk of bias, setting, health behaviour and total KT score