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Table 5 Results of the revised market mix (“To be” scenario)

From: The economic and fiscal impact of incremental use of cell-based quadrivalent influenza vaccine for the prevention of seasonal influenza among healthcare workers in Italy

Revised market mix

Year 1

Year 2

Year 3

Population

203 018

203 018

203 018

Direct healthcare costs

QIVe acquisition costs

€1 063 814.84

€930 837.99

€797 861.13

QIVc acquisition costs

€304 527.15

€456 790.73

€609 054.30

Vaccine administration costs

€1 250 591.50

€1 250 591.50

€1 250 591.50

Total acquisition and administration costs

€2 618 933.49

€2 638 220.21

€2 657 506.93

Influenza cases among vaccinated HCWs

Vaccination with QIVe

3865

3382

2899

Vaccination with QIVc

770

1155

1540

Influenza cases with symptoms among vaccinated HCWs

HCWs with influenza and symptoms

3101

3035

2969

Costs of prescribed influenza drugs

€43 107.76

€42 194.07

€41 280.38

Costs of influenza drugs without prescription

€23 524.64

€23 026.02

€22 527.41

Influenza-related GP visitsa

€15 253.46

€14 930.15

€14 606.85

Total direct healthcare costs

€2 700 819.35

€2 718 370.46

€2 735 921.57

Fiscal impact

QIVe

€110 393.88

€96 594.65

€82 795.41

QIVc

€21 986.73

€32 980.09

€43 973.46

Total fiscal impact

€132 380.61

€129 574.74

€126 768.87

Indirect costs (productivity losses)

QIVe

€1 510 176.26

€1 321 404.23

€1 132 632.19

QIVc

€300 776.03

€451 164.04

€601 552.05

Total indirect costs

€1 810 952.29

€1 772 568.27

€1 734 184.25

Total (direct costs + indirect costs + fiscal impact)

€4 644 152.25

€4 620 513.47

€4 596 874.69

  1. aAssuming that only 35% of HCWs who develop influenza symptoms visit a GP